Abstract 7

Evaluation of serum ferritin as a marker for adult Still's disease activity.

Schwarz-Eywill M Heilig B Bauer H
Breitbart A Pezzutto A

In: Ann Rheum Dis (1992 May) 51(5):683-5

ISSN: 0003-4967

Extremely high serum ferritin values (greater than 10,000
micrograms/l) were detected in two patients with adult Still's
disease. The ferritin concentrations decreased to normal after
adequate treatment. During a one year follow up ferritin
concentration was helpful in monitoring disease activity and guiding
decisions about treatment. Raised concentrations of soluble
interleukin 2 receptors (sCD25) were also found.

Detection of ferritin values above 3000 micrograms/l should lead to the
consideration of Still's disease when there is an acute febrile
illness without evidence for bacterial or viral infections, serum
ferritin being suitable for monitoring treatment.

Registry Numbers: 9007-73-2 (Ferritin)

Institutional address:
      Department of Internal Medicine
      Med Poliklink V
      University of Heidelberg
      Germany.

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