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Comparison of clinical features of childhood vs adult onset Still's disease

Tanaka S  Matsumoto Y  Ohnishi H  
 Maeda M  Nishioka K  Kashiwazaki S  
 Watanabe N  

In: Ryumachi (1991 Oct) 31(5):511-8

ISSN: 0300-9157  (Published in Japanese)

Physical findings, laboratory data, treatments and prognosis were
 investigated in detail using 26 Japanese childhood Still's disease
 (CHSD) patients and 19 Japanese adult onset Still's disease (AOSD)
 patients as the subjects. High spiking fever and arthritis were
 present in all the patients. Seventy and seven percent of CHSD and 53
 percent of AOSD had polyarthritis (the number of joints involved
 being 5 or more during the first 6 months of the disease). A
 comparison of the groups showed no significant difference in the
 initial systemic manifestations except for sore throat (CHSD: AOSD;
 19%: 68%). Initial laboratory data were the same for these groups
 except for serum iron levels (CHSD: AOSD; 20.8 +/- 13.7
 micrograms/dl: 83.0 +/- 54.2 micrograms/dl). As to joints and
 physical prognosis, the results were also the same for CHSD and AOSD
 under the similar treatment.

On the basis of these data, we conclude  that CHSD and AOSD are of the same disease entity so far as the  present clinical features are concerned.

Institutional address:
       Department of Pediatrics
       Kyorin University School of Medicine



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